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Structural evidence for Scc4-dependent localization of cohesin loading
The cohesin ring holds newly replicated sister chromatids together until their separation at anaphase. Initiation of sister chromatid cohesion depends on a separate complex, Scc2(NIPBL)/Scc4(Mau2) (Scc2/4), which loads cohesin onto DNA and determines its localization across the genome. Proper cohesi...
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| Veröffentlicht in: | eLife |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4471937/ https://ncbi.nlm.nih.gov/pubmed/26038942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.06057 |
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