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Structural evidence for Scc4-dependent localization of cohesin loading

The cohesin ring holds newly replicated sister chromatids together until their separation at anaphase. Initiation of sister chromatid cohesion depends on a separate complex, Scc2(NIPBL)/Scc4(Mau2) (Scc2/4), which loads cohesin onto DNA and determines its localization across the genome. Proper cohesi...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Hinshaw, Stephen M, Makrantoni, Vasso, Kerr, Alastair, Marston, Adèle L, Harrison, Stephen C
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471937/
https://ncbi.nlm.nih.gov/pubmed/26038942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.06057
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