Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish

pVHL is a tumor suppressor. The lack of its function leads to various tumors, among which ccRCC (clear cell renal cell carcinoma) has the most serious outcome due to its resistance to chemotherapies and radiotherapies. Although HIF promotes the progression of ccRCC, the precise mechanism by which th...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Kim, Hyejeong Rosemary, Santhakumar, Kirankumar, Markham, Eleanor, Baldera, Davide, Greenald, David, Bryant, Helen E., El-Khamisy, Sherif F., van Eeden, Fredericus J.
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2020
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138166/
https://ncbi.nlm.nih.gov/pubmed/32284789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27521
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