CD45(dim)CD34(+)CD38(−)CD133(+) cells have the potential as leukemic stem cells in acute myeloid leukemia

BACKGROUND: Leukemia stem cells (LSCs) in play an important role in the initiation, relapse, and progression of acute myeloid leukemia (AML), and in the development of chemotherapeutic drug resistance in AML. Studies regarding the detection of LSCs and the development of novel therapies for targetin...

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Vydáno v:BMC Cancer
Hlavní autoři: Heo, Sook-Kyoung, Noh, Eui-Kyu, Ju, Lan Jeong, Sung, Jun Young, Jeong, Yoo Kyung, Cheon, Jaekyung, Koh, Su Jin, Min, Young Joo, Choi, Yunsuk, Jo, Jae-Cheol
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7137473/
https://ncbi.nlm.nih.gov/pubmed/32252668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06760-1
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