Differential CpG DNA methylation in peripheral naïve CD4(+) T-cells in early rheumatoid arthritis patients

BACKGROUND: The genetic risk associated with rheumatoid arthritis (RA) includes genes regulating DNA methylation, one of the hallmarks of epigenetic re-programing, as well as many T-cell genes, with a strong MHC association, pointing to immunogenetic mechanisms as disease triggers leading to chronic...

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Detalles Bibliográficos
Publicado en:Clin Epigenetics
Autores principales: Pitaksalee, R., Burska, A. N., Ajaib, S., Rogers, J., Parmar, R., Mydlova, K., Xie, X., Droop, A., Nijjar, J. S., Chambers, P., Emery, P., Hodgett, R., McInnes, I. B., Ponchel, F.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7137446/
https://ncbi.nlm.nih.gov/pubmed/32264938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00837-1
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