Modulation of peripheral T-cell function by interleukin-7 in rheumatoid arthritis

INTRODUCTION: Interleukin-7 (IL-7) is a cytokine essential for T-cell lymphopoiesis, survival and polarization with an emerging role in autoimmunity. We previously demonstrated reduced levels of circulating IL-7 in rheumatoid arthritis (RA), although high amounts are expressed in joints, suggesting...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Churchman, Sarah M, El-Jawhari, Jehan J, Burska, Agata N, Parmar, Rekha, Goëb, Vincent, Conaghan, Philip G, Emery, Paul, Ponchel, Frederique
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298067/
https://ncbi.nlm.nih.gov/pubmed/25533722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-014-0511-3
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