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Synthesis, biological evaluation and molecular docking analysis of vaniline–benzylidenehydrazine hybrids as potent tyrosinase inhibitors

In this work, 11 novel compounds based on vaniline and benzylidenehydrazine structure were synthesized with various substituents on phenyl aromatic ring of the molecule and evaluated as tyrosinase inhibitors. These new derivatives showed significant anti-tyrosinase activities, among which 4i demonst...

詳細記述

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書誌詳細
出版年:BMC Chem
主要な著者: Iraji, Aida, Adelpour, Tina, Edraki, Najmeh, Khoshneviszadeh, Mahsima, Miri, Ramin, Khoshneviszadeh, Mehdi
フォーマット: Artigo
言語:Inglês
出版事項: Springer International Publishing 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7137441/
https://ncbi.nlm.nih.gov/pubmed/32280949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-020-00679-1
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