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Synthesis, biological evaluation and molecular docking analysis of vaniline–benzylidenehydrazine hybrids as potent tyrosinase inhibitors

In this work, 11 novel compounds based on vaniline and benzylidenehydrazine structure were synthesized with various substituents on phenyl aromatic ring of the molecule and evaluated as tyrosinase inhibitors. These new derivatives showed significant anti-tyrosinase activities, among which 4i demonst...

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Detalhes bibliográficos
Publicado no:BMC Chem
Main Authors: Iraji, Aida, Adelpour, Tina, Edraki, Najmeh, Khoshneviszadeh, Mahsima, Miri, Ramin, Khoshneviszadeh, Mehdi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7137441/
https://ncbi.nlm.nih.gov/pubmed/32280949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-020-00679-1
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