Intranasal perillyl alcohol therapy improves survival of patients with recurrent glioblastoma harboring mutant variant for MTHFR rs1801133 polymorphism

BACKGROUND: Polymorphisms in MTHFR gene influence risk and overall survival of patients with brain tumor. Global genomic DNA (gDNA) methylation profile from tumor tissues is replicated in peripheral leukocytes. This study aimed to draw a correlation between rs1801133 MTHFR variants, gDNA methylation...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Faria, Giselle M., Soares, Igor D. P., D’Alincourt Salazar, Marcela, Amorim, Marcia R., Pessoa, Bruno L., da Fonseca, Clovis O., Quirico-Santos, Thereza
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7137265/
https://ncbi.nlm.nih.gov/pubmed/32264844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06802-8
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