Intranasal perillyl alcohol therapy improves survival of patients with recurrent glioblastoma harboring mutant variant for MTHFR rs1801133 polymorphism

BACKGROUND: Polymorphisms in MTHFR gene influence risk and overall survival of patients with brain tumor. Global genomic DNA (gDNA) methylation profile from tumor tissues is replicated in peripheral leukocytes. This study aimed to draw a correlation between rs1801133 MTHFR variants, gDNA methylation...

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Bibliografiska uppgifter
I publikationen:BMC Cancer
Huvudupphovsmän: Faria, Giselle M., Soares, Igor D. P., D’Alincourt Salazar, Marcela, Amorim, Marcia R., Pessoa, Bruno L., da Fonseca, Clovis O., Quirico-Santos, Thereza
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2020
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7137265/
https://ncbi.nlm.nih.gov/pubmed/32264844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06802-8
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