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Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences

The locus coeruleus (LC), the origin of noradrenergic modulation of cognitive and behavioral function, may play an important role healthy ageing and in neurodegenerative conditions. We investigated the functional significance of age-related differences in mean normalized LC signal intensity values (...

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Vydáno v:Nat Commun
Hlavní autoři: Liu, Kathy Y., Kievit, Rogier A., Tsvetanov, Kamen A., Betts, Matthew J., Düzel, Emrah, Rowe, James B., Howard, Robert, Hämmerer, Dorothea
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136271/
https://ncbi.nlm.nih.gov/pubmed/32249849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15410-w
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