Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences

The locus coeruleus (LC), the origin of noradrenergic modulation of cognitive and behavioral function, may play an important role healthy ageing and in neurodegenerative conditions. We investigated the functional significance of age-related differences in mean normalized LC signal intensity values (...

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Udgivet i:Nat Commun
Main Authors: Liu, Kathy Y., Kievit, Rogier A., Tsvetanov, Kamen A., Betts, Matthew J., Düzel, Emrah, Rowe, James B., Howard, Robert, Hämmerer, Dorothea
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136271/
https://ncbi.nlm.nih.gov/pubmed/32249849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15410-w
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