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Mechanical stretch increases Kv1.5 current through an interaction between the S1–S2 linker and N-terminus of the channel
The voltage-gated potassium channel Kv1.5 plays important roles in atrial repolarization and regulation of vascular tone. In the present study, we investigated the effects of mechanical stretch on Kv1.5 channels. We induced mechanical stretch by centrifuging or culturing Kv1.5-expressing HEK 293 cel...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7136002/ https://ncbi.nlm.nih.gov/pubmed/32122972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011302 |
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