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A study of the efficacy of the bradykinin antagonist, NPC 567, in rhinovirus infections in human volunteers

In a double-blind placebo controlled trial intranasal NPC 567, a bradykinin antagonist, failed to alleviate the symptoms of experimental rhinovirus colds. Indeed, there was evidence that the drug enhanced the symptoms although no irritant effect was detected on the uninfected nasal mucosa.

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Bibliografiske detaljer
Udgivet i:Antiviral Res
Main Authors: Higgins, P.G., Barrow, G.I., Tyrrell, D.A.J.
Format: Artigo
Sprog:Inglês
Udgivet: Published by Elsevier B.V. 1990
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7134172/
https://ncbi.nlm.nih.gov/pubmed/1965113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/0166-3542(90)90052-9
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