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A study of the efficacy of the bradykinin antagonist, NPC 567, in rhinovirus infections in human volunteers

In a double-blind placebo controlled trial intranasal NPC 567, a bradykinin antagonist, failed to alleviate the symptoms of experimental rhinovirus colds. Indeed, there was evidence that the drug enhanced the symptoms although no irritant effect was detected on the uninfected nasal mucosa.

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Detalhes bibliográficos
Publicado no:Antiviral Res
Main Authors: Higgins, P.G., Barrow, G.I., Tyrrell, D.A.J.
Formato: Artigo
Idioma:Inglês
Publicado em: Published by Elsevier B.V. 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7134172/
https://ncbi.nlm.nih.gov/pubmed/1965113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/0166-3542(90)90052-9
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