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Internal ribosome entry sites and dicistronic RNAs in mammalian transgenesis

Modification of the genetic content of cultured cells or of whole animals is now a key strategy in both basic biological research and applied biotechnology. Yet obtaining the desired level and specificity of expression of an introduced gene remains highly problematic. One solution could be to couple...

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Détails bibliographiques
Publié dans:Trends Genet
Auteurs principaux: Mountford, Peter S., Smith, Austin G.
Format: Artigo
Langue:Inglês
Publié: Published by Elsevier Ltd. 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7133804/
https://ncbi.nlm.nih.gov/pubmed/7540337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0168-9525(00)89040-X
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