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Internal ribosome entry sites and dicistronic RNAs in mammalian transgenesis

Modification of the genetic content of cultured cells or of whole animals is now a key strategy in both basic biological research and applied biotechnology. Yet obtaining the desired level and specificity of expression of an introduced gene remains highly problematic. One solution could be to couple...

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Publicat a:Trends Genet
Autors principals: Mountford, Peter S., Smith, Austin G.
Format: Artigo
Idioma:Inglês
Publicat: Published by Elsevier Ltd. 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7133804/
https://ncbi.nlm.nih.gov/pubmed/7540337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0168-9525(00)89040-X
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