Klotho Pathways, Myelination Disorders, Neurodegenerative Diseases, and Epigenetic Drugs

In this review we outline a rationale for identifying neuroprotectants aimed at inducing endogenous Klotho activity and expression, which is epigenetic action, by definition. Such an approach should promote remyelination and/or stimulate myelin repair by acting on mitochondrial function, thereby her...

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Vydáno v:Biores Open Access
Hlavní autoři: Moos, Walter H., Faller, Douglas V., Glavas, Ioannis P., Harpp, David N., Kanara, Iphigenia, Mavrakis, Anastasios N., Pernokas, Julie, Pernokas, Mark, Pinkert, Carl A., Powers, Whitney R., Sampani, Konstantina, Steliou, Kosta, Vavvas, Demetrios G., Zamboni, Robert J., Kodukula, Krishna, Chen, Xiaohong
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc., publishers 2020
Témata:
Comprehensive Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7133426/
https://ncbi.nlm.nih.gov/pubmed/32257625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/biores.2020.0004
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