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Canonical Wnt/β-catenin activity and differential epigenetic marks direct sexually dimorphic regulation of Irx3 and Irx5 in developing mouse gonads

Members of the Iroquois B (IrxB) homeodomain cluster genes, specifically Irx3 and Irx5, are crucial for heart, limb and bone development. Recently, we reported their importance for oocyte and follicle survival within the developing ovary. Irx3 and Irx5 expression begins after sex determination in th...

詳細記述

保存先:
書誌詳細
出版年:Development
主要な著者: Koth, Megan L., Garcia-Moreno, S. Alexandra, Novak, Annie, Holthusen, Kirsten A., Kothandapani, Anbarasi, Jiang, Keer, Taketo, Makoto Mark, Nicol, Barbara, Yao, Humphrey H.-C., Futtner, Christopher R., Maatouk, Danielle M., Jorgensen, Joan S.
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists Ltd 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7132837/
https://ncbi.nlm.nih.gov/pubmed/32108023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.183814
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