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Loss of non‐canonical KCC2 functions promotes developmental apoptosis of cortical projection neurons
KCC2, encoded in humans by the SLC12A5 gene, is a multifunctional neuron‐specific protein initially identified as the chloride (Cl(−)) extruder critical for hyperpolarizing GABA(A) receptor currents. Independently of its canonical function as a K‐Cl cotransporter, KCC2 regulates the actin cytoskelet...
Guardat en:
| Publicat a: | EMBO Rep |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7132201/ https://ncbi.nlm.nih.gov/pubmed/32064760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948880 |
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