SIRT2‐dependent IDH1 deacetylation inhibits colorectal cancer and liver metastases

Protein lysine acetylation affects colorectal cancer (CRC) distant metastasis through multiple pathways. In a previous proteomics screen, we found that isocitrate dehydrogenase 1 (IDH1) is hyperacetylated in CRC primary tumors and liver metastases. Here, we further investigate the function of IDH1 h...

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Publicado no:EMBO Rep
Main Authors: Wang, Bo, Ye, Yingjiang, Yang, Xin, Liu, Boya, Wang, Zhe, Chen, Shuaiyi, Jiang, Kewei, Zhang, Wei, Jiang, Hongpeng, Mustonen, Harri, Puolakkainen, Pauli, Wang, Shan, Luo, Jianyuan, Shen, Zhanlong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7132198/
https://ncbi.nlm.nih.gov/pubmed/32141187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948183
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