SIRT3 regulates cancer cell proliferation through deacetylation of PYCR1 in proline metabolism()

SIRT3 is a major mitochondrial deacetylase, which regulates various metabolic pathways by deacetylation; however, the effect of SIRT3 on proline metabolism is not reported. Pyrroline-5-carboxylate reductase 1 (PYCR1) participates in proline synthesis process by catalyzing the reduction of P5C to pro...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Chen, Shuaiyi, Yang, Xin, Yu, Miao, Wang, Zhe, Liu, Boya, Liu, Minghui, Liu, Lu, Ren, Mengmeng, Qi, Hao, Zou, Junhua, Vucenik, Ivana, Zhu, Wei-Guo, Luo, Jianyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2019
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526305/
https://ncbi.nlm.nih.gov/pubmed/31108370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2019.04.008
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