Metabolic correlates of prevalent mild cognitive impairment and Alzheimer's disease in adults with Down syndrome

INTRODUCTION: Disruption of metabolic function is a recognized feature of late onset Alzheimer's disease (LOAD). We sought to determine whether similar metabolic pathways are implicated in adults with Down syndrome (DS) who have increased risk for Alzheimer's disease (AD). METHODS: We exam...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement (Amst)
Main Authors: Mapstone, Mark, Gross, Thomas J, Macciardi, Fabio, Cheema, Amrita K, Petersen, Melissa, Head, Elizabeth, Handen, Benjamin L, Klunk, William E, Christian, Bradley T, Silverman, Wayne, Lott, Ira T, Schupf, Nicole
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Diagnostic Assessment & Prognosis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7131985/
https://ncbi.nlm.nih.gov/pubmed/32258359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dad2.12028
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