Plasma total-tau and Neurofilament light chain (Nf-L) as diagnostic biomarkers of Alzheimer’s disease dementia and mild cognitive impairment in adults with Down syndrome

BACKGROUND: The need for diagnostic biomarkers of cognitive decline is particularly important among aging adults with Down Syndrome (DS). Growing empirical support has identified the utility of plasma derived biomarkers among neurotypical adults with mild cognitive impairment (MCI) and Alzheimer’s d...

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Veröffentlicht in:J Alzheimers Dis
Hauptverfasser: Petersen, Melissa E., Rafii, Michael S., Zhang, Fan, Hall, James, Julovich, David, Ances, Beau M., Schupf, Nicole, Krinsky-McHale, Sharon J., Mapstone, Mark, Silverman, Wayne, Lott, Ira, Klunk, William, Head, Elizabeth, Christian, Brad, Foroud, Tatiana, Lai, Florence, Rosas, H. Diana, Zaman, Shahid, Wang, Mei-Cheng, Tycko, Benjamin, Lee, Joseph H., Handen, Benjamin, Hartley, Sigan, Fortea, Juan, O’Bryant, Sid
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8273927/
https://ncbi.nlm.nih.gov/pubmed/33337378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-201167
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