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Reduced mouse neurovirulence of poliovirus type 2 lansing antigenic variants selected with monoclonal antibodies

The Lansing strain of poliovirus type 2 is a mouse-adapted virus that induces a fatal paralytic disease in mice after intracerebral inoculation. Our previous results indicated that the mouse-adapted phenotype maps to the Lansing viral capsid. To further define regions of the capsid that are specific...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Virology
Hauptverfasser: La Monica, Nicola, Klipsky, William J., Racaniello, Vincent R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Published by Elsevier Inc. 1987
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7131194/
https://ncbi.nlm.nih.gov/pubmed/2825415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/0042-6822(87)90136-X
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