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Two Amino Acid Changes at the N-Terminus of Transmissible Gastroenteritis Coronavirus Spike Protein Result in the Loss of Enteric Tropism

To study the molecular basis of TGEV tropism, a collection of recombinants between the PUR46-MAD strain of transmissible gastroenteritis coronavirus (TGEV) infecting the enteric and respiratory tracts and the PTV strain, which only infects the respiratory tract, was generated. The recombinant isolat...

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Publicado en:Virology
Autores principales: Ballesteros, M.L., Sánchez, C.M., Enjuanes, L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Academic Press. 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7130969/
https://ncbi.nlm.nih.gov/pubmed/9018137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1006/viro.1996.8344
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