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Biophysical characterization of HRC peptide analogs interaction with heptad repeat regions of the SARS-coronavirus Spike fusion protein core

The Spike (S) protein of SARS-coronavirus (SARS-CoV) mediates viral entry into host cells. It contains two heptad repeat regions, denoted HRN and HRC. We have identified the location of the two interacting HR regions that form the six-helix bundle (B. Tripet, et al, J. Biol. Chem., 279: 20836–20849,...

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Detalhes bibliográficos
Publicado no:J Struct Biol
Main Authors: Yan, Zhe, Tripet, Brian, Hodges, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7129827/
https://ncbi.nlm.nih.gov/pubmed/16765058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2006.03.024
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