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Glycyrrhizin Inhibits Interleukin-8 Production and Nuclear Factor–κ B Activity in Lung Epithelial Cells, but Not Through Glucocorticoid Receptors

This study was designed to examine the glucocorticoid-like inhibitory effect of glycyrrhizin (GL) on interleukin (IL)-8 production in A549 lung epithelial cells. GL, as well as dexamethasone (DEX) inhibited both tumor necrosis factor (TNF)-α –and IL-1β –induced IL-8 production, mRNA expression, and...

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Detalhes bibliográficos
Publicado no:J Pharmacol Sci
Main Authors: Takei, Hironori, Baba, Yuichiro, Hisatsune, Akinori, Katsuki, Hiroshi, Miyata, Takeshi, Yokomizo, Kazumi, Isohama, Yoichiro
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. Production and hosting by Elsevier B.V. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7129470/
https://ncbi.nlm.nih.gov/pubmed/18344608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1254/jphs.FP0072378
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