A retinoic acid receptor agonist Am80 rescues neurons, attenuates inflammatory reactions, and improves behavioral recovery after intracerebral hemorrhage in mice

Am80 (tamibarotene) is a retinoic acid receptor (RAR) agonist clinically available for treatment of acute promyelocytic leukemia. As intracerebral hemorrhage (ICH) accompanies inflammatory reactions in the brain and also because retinoids may suppress activation of microglia, we investigated the eff...

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Detalhes bibliográficos
Main Authors: Matsushita, Hideaki, Hijioka, Masanori, Hisatsune, Akinori, Isohama, Yoichiro, Shudo, Koichi, Katsuki, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049486/
https://ncbi.nlm.nih.gov/pubmed/20551971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.80
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