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In silico models accurately predict in vivo response for IL-6 blockade in head and neck cancer

Malignant features of head and neck squamous cell carcinoma (HNSCC) may be derived from the presence of stem-like cells that are characterized by uniquely high tumorigenic potential. These cancer stem cells (CSCs) function as putative drivers of tumor initiation, therapeutic evasion, metastasis, and...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Nazari, Fereshteh, Oklejas, Alexandra E., Nör, Jacques E., Pearson, Alexander T., Jackson, Trachette L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7127935/
https://ncbi.nlm.nih.gov/pubmed/32041834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-1846
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