A highly pathogenic porcine reproductive and respiratory syndrome virus generated from an infectious cDNA clone retains the in vivo virulence and transmissibility properties of the parental virus

The nucleotide sequence of a highly pathogenic porcine reproductive and respiratory syndrome virus (PRRSV) was determined. Transfection of MARC-145 cells with capped in vitro transcripts derived from a full-length cDNA clone of the viral genome resulted in infectious PRRSV with growth characteristic...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Truong, Ha M, Lu, Z, Kutish, Gerald F, Galeota, Judith, Osorio, Fernando A, Pattnaik, Asit K
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7127741/
https://ncbi.nlm.nih.gov/pubmed/15246270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2004.04.046
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