Characterization of trans‐ and cis‐cleavage activity of the SARS coronavirus 3CL(pro) protease: basis for the in vitro screening of anti‐SARS drugs

Severe acute respiratory syndrome (SARS) has been globally reported. A novel coronavirus (CoV), SARS‐CoV, was identified as the etiological agent of the disease. SARS‐CoV 3C‐like protease (3CL(pro)) mediates the proteolytic processing of replicase polypeptides 1a and 1ab into functional proteins, pl...

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Publicat a:FEBS Lett
Autors principals: Lin, Cheng-Wen, Tsai, Chang-Hai, Tsai, Fuu-Jen, Chen, Pei-Jer, Lai, Chien-Chen, Wan, Lei, Chiu, Hua-Hao, Lin, Kuan-Hsun
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2004
Matèries:
Short Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7127318/
https://ncbi.nlm.nih.gov/pubmed/15358553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2004.08.017
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