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Pathogenic role of HMGB1 in SARS?
High mobility group box 1 protein (HMGB1) is released by necrotic cells or activated macrophages/monocytes, and functions as a late mediator of lethal systemic and local pulmonary inflammation. Passive immunization with anti-HMGB1 antibodies confers significant protection against lethal endotoxemia,...
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| Publicado no: | Med Hypotheses |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Ltd.
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7127179/ https://ncbi.nlm.nih.gov/pubmed/15325019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mehy.2004.01.037 |
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