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Targeting HMGB1 in the treatment of sepsis

INTRODUCTION: Sepsis refers to the host’s deleterious and non-resolving systemic inflammatory response to microbial infections, and represents the leading cause of death in the intensive care unit. The pathogenesis of sepsis is complex, but partly mediated by a newly identified alarmin molecule, the...

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Autori principali: Wang, Haichao, Ward, Mary F., Sama, Andrew E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945414/
https://ncbi.nlm.nih.gov/pubmed/24392842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2014.863876
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