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Enhanced immune responses to viral epitopes by combining macrophage-inducible expression with multimeric display on a Salmonella vector

In this study, the immunogenicity of chimeric 987P fimbriae on a Salmonella vaccine strain was improved by optimizing fimbrial expression. The constitutive tetA promoter and the in vivo activated nirB and pagC promoters were evaluated for their use to express two epitopes of the transmissible gastro...

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Détails bibliographiques
Publié dans:Vaccine
Auteurs principaux: Chen, Huaiqing, Schifferli, Dieter M.
Format: Artigo
Langue:Inglês
Publié: Elsevier Science Ltd. 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7126928/
https://ncbi.nlm.nih.gov/pubmed/11282213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0264-410X(00)00541-7
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