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Enhanced immune responses to viral epitopes by combining macrophage-inducible expression with multimeric display on a Salmonella vector
In this study, the immunogenicity of chimeric 987P fimbriae on a Salmonella vaccine strain was improved by optimizing fimbrial expression. The constitutive tetA promoter and the in vivo activated nirB and pagC promoters were evaluated for their use to express two epitopes of the transmissible gastro...
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| Publicado no: | Vaccine |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Science Ltd.
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7126928/ https://ncbi.nlm.nih.gov/pubmed/11282213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0264-410X(00)00541-7 |
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