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Salmonella Vaccine Vectors Displaying Delayed Antigen Synthesis In Vivo To Enhance Immunogenicity

We have developed a regulated delayed antigen synthesis (RDAS) system for use in recombinant attenuated Salmonella vaccine (RASV) strains to enhance immune responses by reducing the adverse effects of high-level antigen synthesis. This system includes a chromosomal repressor gene, lacI, expressed fr...

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Main Authors: Wang, Shifeng, Li, Yuhua, Scarpellini, Giorgio, Kong, Wei, Shi, HuoYing, Baek, Chang-Ho, Gunn, Bronwyn, Wanda, Soo-Young, Roland, Kenneth L., Zhang, Xin, Senechal-Willis, Patti, Curtiss, Roy
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937466/
https://ncbi.nlm.nih.gov/pubmed/20605977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00444-10
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