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Evaluating enzyme activities and structures of DUBs

Ubiquitin signaling requires tight control of all aspects of protein ubiquitination, including the timing, locale, extent, and type of modification. Dysregulation of any of these signaling features can lead to severe human disease. One key mode of regulation is through the controlled removal of the...

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Pubblicato in:Methods Enzymol
Autori principali: Pruneda, Jonathan N., Komander, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7126802/
https://ncbi.nlm.nih.gov/pubmed/30850058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.01.001
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