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Functional Evolution of PLP-dependent Enzymes based on Active-Site Structural Similarities

Families of distantly related proteins typically have very low sequence identity, which hinders evolutionary analysis and functional annotation. Slowly evolving features of proteins, such as an active site, are therefore valuable for annotating putative and distantly related proteins. To date, a com...

詳細記述

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書誌詳細
主要な著者: Catazaro, Jonathan, Caprez, Adam, Guru, Ashu, Swanson, David, Powers, Robert
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177364/
https://ncbi.nlm.nih.gov/pubmed/24920327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24624
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