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Fine-tuning of type I IFN-signaling in microglia — implications for homeostasis, CNS autoimmunity and interferonopathies

Type I interferons (IFN) are pleiotropic cytokines originally described as molecules used for communication between cells to trigger the protective defenses against viral infections. Upon activation, type I IFN can be produced locally in the central nervous system (CNS) from a number of different ce...

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Detalhes bibliográficos
Publicado no:Curr Opin Neurobiol
Main Authors: Goldmann, Tobias, Blank, Thomas, Prinz, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7126514/
https://ncbi.nlm.nih.gov/pubmed/26397019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conb.2015.09.003
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