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The Matrix Protein VP40 from Ebola Virus Octamerizes into Pore-like Structures with Specific RNA Binding Properties
The Ebola virus membrane-associated matrix protein VP40 is thought to be crucial for assembly and budding of virus particles. Here we present the crystal structure of a disk-shaped octameric form of VP40 formed by four antiparallel homodimers of the N-terminal domain. The octamer binds an RNA tririb...
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| Publicat a: | Structure |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cell Press. Published by Elsevier Ltd.
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7126486/ https://ncbi.nlm.nih.gov/pubmed/12679020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0969-2126(03)00050-9 |
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