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The Matrix Protein VP40 from Ebola Virus Octamerizes into Pore-like Structures with Specific RNA Binding Properties

The Ebola virus membrane-associated matrix protein VP40 is thought to be crucial for assembly and budding of virus particles. Here we present the crystal structure of a disk-shaped octameric form of VP40 formed by four antiparallel homodimers of the N-terminal domain. The octamer binds an RNA tririb...

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發表在:Structure
Main Authors: Gomis-Rüth, F.Xavier, Dessen, Andréa, Timmins, Joanna, Bracher, Andreas, Kolesnikowa, Larissa, Becker, Stephan, Klenk, Hans-Dieter, Weissenhorn, Winfried
格式: Artigo
語言:Inglês
出版: Cell Press. Published by Elsevier Ltd. 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7126486/
https://ncbi.nlm.nih.gov/pubmed/12679020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0969-2126(03)00050-9
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