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Antileishmanial activity of MDL 28170, a potent calpain inhibitor

Several calpain inhibitors are under development and some are useful agents against important human pathogens. We therefore investigated the effect of MDL 28170, a potent calpain inhibitor, on the growth of Leishmania amazonensis. After 48 h of treatment, the inhibitor exhibited a dose-dependent ant...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Antimicrob Agents
Hauptverfasser: d’Avila-Levy, Claudia M., Marinho, Fernanda A., Santos, Lívia O., Martins, Juliana L., Santos, André L.S., Branquinha, Marta H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier B.V. and the International Society of Chemotherapy. 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7126437/
https://ncbi.nlm.nih.gov/pubmed/16842979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijantimicag.2006.03.021
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