1H-1,2,3-triazole tethered isatin-ferrocene conjugates: Synthesis and in vitro antimalarial evaluation

1H-1,2,3-triazole tethered isatin-ferrocene conjugates were synthesized and evaluated for their antiplasmodial activities against chloroquine-susceptible (3D7) and chloroquine-resistant (W2) strains of Plasmodium falciparum. The conjugates 5f and 5h with an optimum combination of electron-withdrawin...

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Publicado en:Eur J Med Chem
Autores principales: Kumar, Kewal, Pradines, Bruno, Madamet, Marilyn, Amalvict, Rémy, Benoit, Nicolas, Kumar, Vipan
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier Masson SAS. 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7126053/
https://ncbi.nlm.nih.gov/pubmed/25440881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2014.10.024
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