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Identification of novel ligands for the RNA pseudoknot that regulate −1 ribosomal frameshifting

In many viruses, −1 ribosomal frameshifting (−1RF) regulates synthesis of proteins and is crucial for virus production. An RNA pseudoknot is one of the essential components of the viral −1RF system. Thermodynamic or kinetic control of pseudoknot folding may be important in regulating the efficiency...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Park, So-Jung, Jung, Young Hoon, Kim, Yang-Gyun, Park, Hyun-Ju
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7125880/
https://ncbi.nlm.nih.gov/pubmed/18321712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.02.025
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