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Cyclophilin inhibitors as antiviral agents
Cyclophilins (Cyps) are ubiquitous proteins that effect the cis–trans isomerization of Pro amide bonds, and are thus crucial to protein folding. CypA is the most prevalent of the ∼19 human Cyps, and plays a crucial role in viral infectivity, most notably for HIV-1 and HCV. Cyclophilins have been sho...
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| Publicado en: | Bioorg Med Chem Lett |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Elsevier Ltd.
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7125669/ https://ncbi.nlm.nih.gov/pubmed/23849880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.05.101 |
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