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Expanding the genetic code: selection of efficient suppressors of four-base codons and identification of “shifty” four-base codons with a library approach in Escherichia coli

Naturally occurring tRNA mutants are known that suppress +1 frameshift mutations by means of an extended anticodon loop, and a few have been used in protein mutagenesis. In an effort to expand the number of possible ways to uniquely and efficiently encode unnatural amino acids, we have devised a gen...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Magliery, Thomas J, Anderson, J.Christopher, Schultz, Peter G
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press. 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7125544/
https://ncbi.nlm.nih.gov/pubmed/11273699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1006/jmbi.2001.4518
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