Llwytho...

Design, synthesis, and evaluation of 3C protease inhibitors as anti-enterovirus 71 agents

Human enterovirus (EV) belongs to the picornavirus family, which consists of over 200 medically relevant viruses. A peptidomimetic inhibitor AG7088 was developed to inhibit the 3C protease of rhinovirus (a member of the family), a chymotrypsin-like protease required for viral replication, by forming...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bioorg Med Chem
Prif Awduron: Kuo, Chih-Jung, Shie, Jiun-Jie, Fang, Jim-Min, Yen, Guei-Rung, Hsu, John T.-A., Liu, Hun-Ge, Tseng, Sung-Nain, Chang, Shih-Cheng, Lee, Ching-Yin, Shih, Shin-Ru, Liang, Po-Huang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier Ltd. 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7125518/
https://ncbi.nlm.nih.gov/pubmed/18583140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.06.015
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!