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Design and characterization of novel dual Fc antibody with enhanced avidity for Fc receptors
Monoclonal antibodies (mAbs) have become an important class of therapeutics, particularly in the realm of anticancer immunotherapy. While the two antigen-binding fragments (Fabs) of an mAb allow for high-avidity binding to molecular targets, the crystallizable fragment (Fc) engages immune effector e...
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| Publicado no: | Proteins |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7125023/ https://ncbi.nlm.nih.gov/pubmed/31702857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25853 |
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