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Activin type II receptor signaling in cardiac aging and heart failure

Activin type II receptor (ActRII) ligands have been implicated in muscle wasting in aging and disease. However, the role of these ligands and ActRII signaling in the heart remains unclear. Here, we investigated this catabolic pathway in human aging and heart failure (HF) using circulating follistati...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Roh, Jason D., Hobson, Ryan, Chaudhari, Vinita, Quintero, Pablo, Yeri, Ashish, Benson, Mark, Xiao, Chunyang, Zlotoff, Daniel, Bezzerides, Vassilios, Houstis, Nicholas, Platt, Colin, Damilano, Federico, Lindman, Brian R., Elmariah, Sammy, Biersmith, Michael, Lee, Se-Jin, Seidman, Christine E., Seidman, Jonathan G., Gerszten, Robert E., Lach-Trifilieff, Estelle, Glass, David J., Rosenzweig, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7124007/
https://ncbi.nlm.nih.gov/pubmed/30842316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aau8680
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