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Interferon-induced IDO1 mediates radiation resistance and is a therapeutic target in colorectal cancer

Colorectal cancer (CRC) is a major cause of mortality worldwide. Chemotherapy and radiation remain standard treatment for locally advanced disease, with current immune-targeting therapies applying to only a small subset of patients. Expression of the immuno-oncology target indoleamine 2,3 dioxygenas...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Chen, Baosheng, Alvarado, David M, Iticovici, Micah, Kau, Nathan S, Park, Haeseong, Parikh, Parag J, Thotala, Dinesh, Ciorba, Matthew A
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7123802/
https://ncbi.nlm.nih.gov/pubmed/32127391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-19-0282
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